| Captain Leland Stottlemeyer? (125 episodes 2002-2009) | 泰德·拉文
 | |
| Lt. Randall Disher? (125 episodes 2002-2009) | Jason Gray-Stanford | |
| Adrian Monk? (125 episodes 2002-2009) | 托尼·夏尔赫布
 | |
| Sharona Fleming (40 episodes 2002-2009) | Bitty Schram
 | |
| Natalie Teeger? (87 episodes 2005-2009) | 特蕾勒·霍华德
 | |
| Dr. Charles Kroger? (44 episodes 2002-2009) | Stanley Kamel
 | |
| Julie Teeger (25 episodes 2005-2009) | 艾米·克拉克
 | |
| Benjy Fleming? (15 episodes 2002-2004) | Kane Ritchotte | |
| Trudy Monk? (10 episodes 2004-2009) | 梅罗拉·哈丁
 | |
| Benjy Fleming (7 episodes 2002) | Max Morrow | |
| Harold Krenshaw? (9 episodes 2004-2009) | Tim Bagley | |
| Dr. Neven Bell (14 episodes 2008-2009) | 赫克托·埃里仲杜
 | |
| Kevin Dorfman (6 episodes 2004-2009) | Jarrad Paul
 | |
| Uniform Cop? (5 episodes 2003-2004) | David Stanford | |
| Leigh? (5 episodes 2002-2009) | 布鲁克·亚当斯
 | |
| Karen Stottlemeyer (4 episodes 2003-2006) | 格伦妮·海德利
 | |
| Linda Fusco (4 episodes 2006-2008) | 莎朗·劳伦斯
 | |
| Reporter? (4 episodes 2002) | J.C. Kenny | |
| Sgt. Cargill? (4 episodes 2002) | David Sparrow
 | |
| Trudy Monk (4 episodes 2002-2003) | Stellina Rusich | |
