| 角色 | 饰演者 | 角色介绍 |
| Dr. Venture?/ ... (28?episodes 2003-2006) | James Urbaniak | |
| Brock Samson?/ ... (28?episodes 2003-2006) | 帕特里克·沃伯顿 | |
| Dean Venture?/ ... (28?episodes 2003-2006) | Michael Sinterniklaas | |
| Hank Venture?/ ... (28?episodes 2003-2006) | Christopher McCulloch | |
| Dr. Girlfriend?/ ... (22?episodes 2004-2006) | Doc Hammer | |
| Dr. Orpheus?/ ... (17?episodes 2004-2006) | Steven Rattazzi | |
| Triana Orpheus?/ ... (14?episodes 2003-2006) | Lisa Hammer | |
| Dr. Jonas Venture?/ ... (10?episodes 2004-2006) | Paul Boocock | |
| Molotov Cocktease?/ ... (8?episodes 2004-2006) | Mia Barron | |
| Kim?/ ... (8?episodes 2004-2006) | Nina Hellman | |
| Agent Hauser?/ ... (6?episodes 2006) | Brendon Small | |
| Jefferson Twilight?/ ... (6?episodes 2004-2006) | Charles Parnell | |
| The Alchemist?/ ... (5?episodes 2006) | Dana Snyder | |
| Baron ünderbheit?/ ... (4?episodes 2004-2006) | T. Ryder Smith | |
| Mexican University Administrator?/ ... (3?episodes 2003-2004) | Richard Liebmann-Smith | |
| Mrs. Manstrong?/ ... (3?episodes 2006) | Joanna Adler | |
| Professor Impossible (2?episodes 2004-2006) | 史蒂芬·科拜尔 |
