| 角色 | 饰演者介绍 |
| John Crowley | 布兰登·费舍 |
| Dr. Robert Stonehill | 哈里森·福特 |
| Aileen Crowley | 凯丽·拉塞尔 |
| Megan Crowley | Meredith Droeger |
| Patrick Crowley | Diego Velazquez |
| John Crowley Jr. | Sam M. Hall |
| Dr. Kent Webber | 杰瑞德·哈里斯 |
| CEO Erich Loring | 帕特里克·波查 |
| Pete Sutphen | 阿兰·卢克 |
| Dr. Renzler | David Clennon |
| Sal | 迪·沃伦斯-斯通 |
| Marcus Temple | 考特尼·万斯 |
| Wendy Temple | Ayanna Berkshire |
| Dr. Preston | P.J. Byrne |
| Dr. Allegria | Andrea White |
| Niles | G.J. Echternkamp |
| Vinh Tran | Vu Pham |
| Cal Dunning | Derek Webster |
| Renzler Scientist #1 | Jana Lee Hamblin |
| Senior Scientist | Shelly Lipkin |
| Researcher (as Chris Harder) | Christopher D. Harder |
| Security Officer | Eric Derovanessian |
| Reception Nurse | Patricia Ferguson |
| Day Nurse (Jane) | Jeanette McMahon |
| Julia | Brennan Claire |
| Night Nurse (Marcy) | Tra'Renee Chambers |
| Maria | Quigley Provost-Landrum |
| ICU Nurse | Kimberly Howard |
| Dr. Waldman | Lily Mariye |
| Day Nurse (Kate) | Sherilyn Lawson |
| ICU Doctor | Eric Martin Reid |
| Stonehill?s Secretary | Sharonlee McLean |
| Van Driver | Bryce Flint-Sommerville |
| Nell Madden | Jeanine Jackson |
| Webber's Assistant | Gavin Bristol |
