| 角色 | 饰演者介绍 |
| James Ubriacco | 约翰·特拉沃塔 |
| Mollie Ubriacco | 柯尔斯蒂·艾利 |
| Rosie | 奥林匹亚·杜卡基斯 |
| Albert | 乔治·席格 |
| Grandpa | Abe Vigoda |
| Mikey (voice) | 布鲁斯·威利斯 |
| Rona | 吐温克·卡潘 |
| Mikey | Jason Schaller |
| Mikey | Jaryd Waterhouse |
| Mikey | Jacob Haines |
| Mikey | Christopher Aydon |
| Melissa | Joy Boushel |
| Dr. Fleisher | 唐·戴维斯 |
| Lou | Louis Heckerling |
| Secretary | Brenda Crichlow |
| Salesgirl | Andrea Mann |
| Cab Stealer | Douglas Tuck |
| Street Worker | Alex Bruhanski |
| Admitting Clerk | Casey Grant |
| Hospital Worker | Oscar B. Ramos |
| Orderly | Aurelio Dinunzio |
| Admitting Doctor | Jeff Irvine |
| Nurse | Shirley Barclay |
| Drug Doctor | William B. Davis |
| Mr. Impatience | David Berner |
| Mr. Anal | Jerry Wasserman |
| Carrie | Daliah Bache |
| Lupe | Zena Darawalla |
| Harry | Nicholas Rice |
| Mr. Russ | 尼尔·伊斯雷尔 |
| Director | 布鲁·曼库玛 |
| Home Orderly | William Britos |
| Burly Orderly | Dee Jay Jackson |
| Lady | Isa Burner |
| Lady | Bea Cartwell |
| Lady | Eleanor Haines |
| Little Girl | Mollie Israel |
| Little Boy | Ryan McIntosh |
| Pilot Friend | Gerry Bean |
| Pilot Friend | Deryl Hayes |
| Ester | Enid Saunders |
| Silly Baby | Nicole Stevens |
| Baby Megan | Christy Smith |
| Sand Box Baby | Sabrina Bailey |
