| 角色 | 饰演者介绍 |
| Lucy Eleanor Moderatz | 桑德拉·布洛克 |
| Jack Callaghan | 比尔·普尔曼 |
| Peter Callaghan | 彼得·盖勒 |
| Elsie | 格莱妮丝·约翰斯 |
| Joe 'Joey' Fusco Jr. | 迈克尔·瑞斯玻利 |
| Ashley Bartlett Bacon | 艾利·沃克 |
| Mary Callaghan | 莫尼卡·凯娜 |
| Dr. Rubin | 迪克·库萨克 |
| Midge Callaghan | Micole Mercurio |
| Jerry Wallace | Jason Bernard |
| Nurse Wanda | Ruth Rudnick |
| Celeste | Marcia Wright |
| Man in Peter's Room | Thomas Q. Morris |
| Doorman | Bernie Landis |
| Dalton Clarke | James Krag |
| Orderly | Rick Worthy |
| Intern | Marc Grapey |
| Priest | Joel Hatch |
| Joe Fusco Sr. | Mike Bacarella |
| Hot Dog Vendor | Peter Siragusa |
| Man in Church | Gene Janson |
| Phyllis | Krista Lally |
| Cop at ICU | Kevin Gudahl |
| Blood Donor Nurse | Ann Whitney |
| Admitting Nurse | Margaret Travolta |
| Ashley's Husband | Shea Farrell |
| Beth | Kate Reinder |
| Celeste's Friend | Susan Messing |
| Lucy's Father | Richard Pickren |
| Young Lucy | Megan Schaiper |
| Mailman | Dobie Maxwell |
| Bit (uncredited) | Robert Minkoff |
| Ox Callaghan | 彼得·伯耶尔 |
