| 角色 | 饰演者 | 角色介绍 |
| Marmaduke (voice) | 欧文·威尔逊 | |
| Mazie (voice) | 艾玛·斯通 | |
| Carlos (voice) | 乔治·洛佩兹 | |
| Marmaduke | George | |
| Marmaduke | Spirit | |
| Mazie | Huck | |
| Carlos | Mai Tai | |
| Giuseppe (voice) | 克里斯托夫·梅兹-普莱瑟  | |
| Giuseppe | Dolly | |
| Raisin (voice) | 史蒂夫·库根 | |
| Raisin | Tyler | |
| Jezebel (voice) (as Fergie) | 菲姬 | |
| Jezebel | Blake | |
| Bosco (voice) | 基弗·萨瑟兰 | |
| Bosco | Axel | |
| Thunder (voice) | 小达蒙·威亚斯 | |
| Thunder | Sandy | |
| Lightning (voice) | 马龙·韦恩斯 | |
| Lightning | Bud | |
| Chupadogra (voice) | 山姆·艾里奥特 | |
| Chupadogra | Oswald | |
| Phil Winslow | 李·佩斯 | |
| Debbie Winslow | 朱迪·格雷尔 | |
| Barbara Winslow | 卡洛琳·珊珊 | |
| Brian Winslow | Finley Jacobsen | |
| Sarah Winslow | Mandy Haines | |
| Sarah Winslow | Milana Haines | |
| Anton Harrison | 大卫·威廉姆斯 | |
| Don Twombly | 威廉姆·H·梅西 | |
| Bodie | Glenn McCuen | |
| Buff Owner | Frank Topol | |
| Giant Teenage Boy | Graylen Cameron | |
| Dog Catcher | Alex Rockhill | |
| Skater Boy #1 | Cameron Cowles | |
| Skater Boy #2 | John Daily | |
| Skater Boy #3 | Tyler Abiew | |
| Jessica | 海瑟·多克森 | |
| Male Executive (as Ashley Liu) | Ash Lee | |
| Brunette Girl | Madison Desjarlais | |
| Redhead Girl | Erin Kerr | |
| 3rd OC Girl (as Nicole Munoz) | Nicole Mu?oz | |
| Jock | Christopher Attadia | |
| Man on Bench | Jason Bryden |
