| 角色 | 饰演者介绍 |
| Mr. Popper | 金·凯瑞 |
| Amanda | 卡拉·古奇诺 |
| Mrs. Van Gundy | 安吉拉·兰斯伯瑞 |
| Pippi | 奥菲利亚·拉维邦德 |
| Janie | 玛德琳·卡罗尔 |
| Nat Jones | 克拉克·格雷格 |
| Mr. Gremmins | 杰弗里·塔伯 |
| Kent | 大卫·克鲁霍尔特兹 |
| Franklin | 菲利浦·贝克·霍尔 |
| Billy | Maxwell Perry Cotton |
| Rick | 詹姆士·塔珀 |
| Reader | Dominic Chianese |
| Yates (as William C. Mitchell) | William Charles Mitchell |
| Tommy's Mom | Kelli Barrett |
| Young Tommy Popper #2 | Dylan Clark Marshall |
| Young Tom Popper Sr (voice) | 布莱恩T·德莱尼 |
| Gremmins's Secretary | Elaine Cusick |
| Town Car Driver (as Harlin C. Kearsley) | Harlin Kearsley |
| Daryl | Desmin Borges |
| Reginald | Lee Moore |
| Tito | Dominic Colon |
| Freddy | Jeff Lima |
| Klaus | Frank Ciornei |
| Arnold | J.R. Horne |
| Arctic Friend (voice) | Matthew Wolf |
| Animal Control Guy | Andrew Stewart-Jones |
| Fish & Game Officer | 詹姆斯·陈 |
| Marine & Waterfowl Officer | Rafael Osorio |
| Sanitation Officer | Curtis Shumaker |
| Random Man on Street | Joe D'Onofrio |
| Nanny | Olga Merediz |
| Tavern Hostess | Betsy Aidem |
| Fishmonger (as Angel L. Caban) | Angel Caban |
| Young Developer | Chris Beetem |
| Old Tom Popper Sr. (voice) | Charles L. Campbell |
